Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype
Abstract Background The Warburg phenotype in cancer cells click here has been long recognized, but there is still limited insight in the consecutive metabolic alterations that characterize its establishment.We obtained better understanding of the coupling between metabolism and malignant transformation by studying mouse embryonic fibroblast-derived